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Kanamycin nucleotidyltransferase : ウィキペディア英語版 | Kanamycin nucleotidyltransferase
In molecular biology, kanamycin nucleotidyltransferase (KNTase) is an enzyme which is involved in conferring resistance to aminoglycoside antibiotics. It catalyses the transfer of a nucleoside monophosphate group from a nucleotide to kanamycin. This enzyme is dimeric with each subunit being composed of two domains. The C-terminal domain contains five alpha helices, four of which are organised into an up-and-down alpha helical bundle. Residues found in this domain may contribute to this enzyme's active site. ==References==
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